Dr. Jaffrani has practiced as an Interventional cardiologist in the United States of America for over 13 years. He has worked at Louisiana heart hospital, Baylor heart hospital Plano, Medical City Las Colinas hospital, Richardson Medical Center, and Dallas Medical Center. He moved back to Pakistan in June 2021 and joined South City Hospital as an Interventional cardiologist. Dr. Jaffrani performs cardiac catheterization, coronary angioplasty/stents, peripheral angiogram and angioplasty, pacemaker, and automated implantable defibrillators. He also performs trans oesophageal echocardiogram. Dr. Jaffrani has vast experience in treating complex patients with different heart rhythm problems.

Dr. Jaffrani does outpatient and inpatient services.